Do not hesitate to contact me to get a detailed and regularly updated resume at : bastard.karine@gmail.com
- 2006-present: Post-Doctoral Fellowship in Levitt group at Stanford University.
- 2002-2005: Ph. D. thesis in Molecular Modeling, University of Paris 7
- 2002: Master in Bioinformatics and Molecular Modeling, University of Paris 7
- 2000: Bachelor in Biochemistry, University of Nantes, France
- January 2006 to present: Marie Curie Post-Doctoral Fellowship in Prof. Michael Levitt's group in the Department of Structural Biology at Stanford University. "Simulation studies of the relationship between ligand induced rearrangements of enzyme
loops and high ligand selectivity".
- September 2005 to december 2005: GGMM Fellowship in the Laboratoire de Biochimie Theorique with Dr. Chantal Prevost, IBPC, Paris. "Modeling the RecA Nucleoprotein Filament".
- February 2002 to september 2005: Ph. D. thesis in Molecular Modeling, University of Paris 7, under the supervision of Dr. Chantal Prevost, Laboratoire de Biochimie Theorique, Institut de Biologie Physico-Chimique, Paris. "Flexible Macromolecular Docking: the Mean-Field Theory Applied to the Loop Remodeling Problem".
- June to august 2004: Fellowship in the School of Engineering and Science, International University Bremen, Germany (grant from the European Science Foundation) under the supervision of Prof. Martin Zacharias: "Integration of two complementary docking programs accounting for protein surface remodelling during association".
- June to august 2001: Master research in the Laboratoire de Genetique et Developpement, University of Rennes, France, under the supervision of Dr. Catherine Le Goff: "Determination of the GSPT1 protein function in the mouse using genetic and bioinformatic tools".
- January to april 2001: Master research in the Laboratoire de Biocatalyse, University of Nantes, France, under the supervision of Prof. Charles Tellier: "Bioinformatics: search for genes encoding an etherase in the Archaea genome".
1. K. Bastard, A. Thureau, R. Lavery and C. Prevost. Docking macromolecules with flexible segments. J. Comput. Chem. 2003, 24(15), 1910-1920.
2. K. Bastard, C. Prevost and M. Zacharias. Accounting for loop flexibility during protein-protein docking. Proteins. 2006, 62(4), 956-969.
3. K. Bastard and C. Prevost. Flexible macromolecular docking: An overview of recent progress. Recent Adv. in Structural Bioinformatics, Research signpost. 2007, 249-275
4. B. O. Villoutreix, K. Bastard, O. Sperandio, R. Fahraeus, J.L. Poyet, F. Calvo, B. Deprez, M. A. Miteva. In silico-in vitro screening of protein-protein interface: towards the generation of tomorrow new therapeutics. Curr Pharm Biotechnol. 2008, 9(2):103-22
5. S. Loriot, S. Sachdeva, K. Bastard, C. Prevost and F. Cazals. On the Characterization and Selection of Diverse Conformational Ensembles, with Applications to Flexible Docking. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 24 Jun. 2009.
6. D. Sharma*, K. Bastard*, L.A. Guethlein, PJ. Norman, N. Yawata, M. Yawata, Pando M, Thananchai H, Dong T, Rowland-Jones S, Brodsky FM, Parham P. Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402. J Immunol. 2009 Oct 1;183(7):4569-82.
(* egual contribution)