List of Michael Levitt's Twenty Best Papers (May 2004)

A paper Levitt considers to be one of his twenty best is marked [a+]; a paper he considers to be of his ten best is marked [a]. A paper that has been cited over 200 times is marked [**]; a paper cited over 100 times is marked [*].  Updating this list is hard as one has to delete papers that used to be best…

  1. [a+] Levitt, M. and A. Warshel. Computer Simulation of Protein Folding. Nature 253, 694-698 (1975). [**]
  2. [a+] Warshel, A. and M. Levitt. Theoretical Studies of Enzymic Reactions: Dielectric, Electrostatic and Steric Stabilization of the Carbonium Ion in the Reaction of Lysozyme. J. Mol. Biol. 103, 227-249 (1976). [**]
  3. [a+] Levitt, M. A Simplified Representation of Protein Conformations for Rapid Simulation of Protein Folding. J. Mol. Biol. 104, 59-107 (1976). [**]
  4. [a+] Levitt, M. and C. Chothia. Structural Patterns in Globular Proteins. Nature 261, 552-558 (1976). [**]
  5. [a+] Levitt, M. Protein Folding by Restrained Energy Minimization and Molecular Dynamics. J. Mol. Biol. 170, 723-764 (1983). [*]
  6. [a+] Levitt, M. and R. Sharon. Accurate Simulation of Protein Dynamics in Solution. Proc. Natl. Acad. Sci. USA. 85, 7557-7561 (1988). [**]
  7. [a+] Levitt, M. Accurate Modelling of Protein Conformation by Automatic Segment Matching. J. Mol. Biol. 226, 507-533 (1992). [*]
  8. [a+] Daggett, V. and M. Levitt. Protein Unfolding Pathways Explored Through Molecular Dynamics Simulations. J. Mol. Biol. 232 600-618 (1993).
  9. [a+] Park, B. and M. Levitt. Energy Functions that Discriminate X-ray and Near-Native Folds from Well-Constructed Decoys. J. Mol. Biol., 258, 367-392 (1996).
  10.  [a+] Xia, Y and M. Levitt. Roles of Mutation and Recombination in the Evolution of Protein Thermodynamics. Proc Natl. Acad. Sci U S A. 99: 10382-10387 (2002).
  11. [a] Levitt, M. and S. Lifson. Refinement of Protein Conformations Using a Macromolecular Energy Minimization Procedure. J. Mol. Biol. 46, 269-279 (1969). [**]
  12. [a] Levitt, M. Detailed Molecular Model for Transfer Ribonucleic Acid. Nature 224, 759-763 (1969). [**]
  13. [a] Jack, A. and M. Levitt. Refinement of Large Structures by Simultaneous Minimization of Energy and R Factor. Acta Crystallogr. A34, 931-935 (1978). [**]
  14. [a] Levitt, M. How Many Base-Pairs per Turn Does DNA have in Solution and in Chromatin? Some Theoretical Calculations. Proc. Nat. Acad. Sci. USA 75, 640-644 (1978). [**]
  15. [a] Levitt, M. Molecular Dynamics of Native Protein: I. Computer Simulation of Trajectories. J. Mol. Biol. 168, 595-620 (1983). [**]
  16. [a] Levitt, M., C. Sander and P.S. Stern. Protein Normal-Mode Dynamics: Trypsin Inhibitor, Crambin, Ribonuclease and Lysozyme. J.Mol.Biol. 181, 423-447 (1985). [**]
  17. [a] Levitt, M. and M.F. Perutz. Aromatic Rings Act as Hydrogen Bond Acceptors. J. Mol. Biol. 201, 751-754 (1988). [**]
  18. [a] Hinds, D. A. and M. Levitt. Exploring Conformational Space with a Simple Lattice Model for Protein Structure. J. Mol. Biol. 243, 668-682 (1994).
  19. [a] Raschke, T.M., Tsai, J. and M. Levitt. Quantification of the Hydrophobic Interaction by Simulations of the Aggregation of Small Hydrophobic Solutes in Water. Proc. Natl. Acad. Sci., 98, 5965-5660 (2001). ).]
  20. [a] Keasar, C. and M. Levitt.  A Novel Approach to Decoy Set Generation: Designing a Physical Energy Function Having Local Minima with Native Structure Characteristics. J. Mol. Biol. 329, 159-174 (2003).

Copyright Michael Levitt. (Updated May 2004)